Protein Name:
Kinesin-like protein KIF2A
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UniprotKB/SwissProt ID: O00139 (O00139)
Gene Name:
KIF2A
Organism: Homo sapiens (Human)
Function: Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O00139
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
199 |
DATNPNYEIM C MIRDFRGSLD |
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| 2 |
309 |
ETIFERGMAT C FAYGQTGSGK |
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| 3 |
406 |
VVGLQEREVK C VEDVLKLIDI |
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| 4 |
420 |
VLKLIDIGNS C RTSGQTSANA |
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| 5 |
525 |
DSFIGENSRT C MIATISPGMA |
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