UniprotKB/SwissProt ID: O00092 (O00092)
Gene Name:
phyA
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Catalyzes the phosphate monoester hydrolysis of phytic acid (myo-inositol hexakisphosphate), which results in the stepwise formation of myo-inositol pentakis-, tetrakis-, tris-, bis-, and monophosphates, as well as the liberation of inorganic phosphate (PubMed:9143104, PubMed:9925555). Myo-inositol 2-monophosphate is the end product (PubMed:9143104, PubMed:9925555). Has a broad substrate specificity and is also able to dephosphorylate other classic acid phosphatase substrates such as p-nitrophenyl phosphate, phenyl phosphate, fructose 1,6-bisphosphate, fructose 6-phosphate, glucose 6-phosphate, ribose 5-phosphate, alpha-glycerophosphate, beta-glycerophosphate, 3-phosphoglycerate, phosphoenolpyruvate, as well as ADP and ATP (PubMed:9143104, PubMed:9925555)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted
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