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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Fatty acid hydroperoxide lyase, chloroplastic

UniprotKB/SwissProt ID: K4CF70 (K4CF70)

Gene Name: HPL

Organism: Solanum lycopersicum (Tomato)

Function: Cytochrome P450 of the CYP74B subfamily involved in the biosynthesis of traumatin and C6 aldehydes (PubMed:10859201, PubMed:10923789). Metabolizes 13- but not 9-hydroperoxides of linoleic and linolenic acids (PubMed:10859201, PubMed:10923789). Can use 15S-hydroperoxy-11(Z),13(E),17(Z)-eicosatrienoic acid (15-HPET) and 13S-hydroperoxy-9(Z),11(E),15(Z)-octadecatrienoic acid (13-HPOT) as substrates, but only 5% activity with 13S-hydroperoxy-9(Z),11(E)-octadecadienoic acid (13-HPOD) (PubMed:10859201). Produces n-hexanal and 12-oxo-9(Z)-dodecanoic acid from 13-HPOD (PubMed:10923789)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Plastid, chloroplast outer membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001128 Cyt_P450
IPR002403 Cyt_P450_E_grp-IV
IPR036396 Cyt_P450_sf

The S-nitrosylation sites of K4CF70

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 118 SVVYTGDMRV C AYLDTSEPKH