UniprotKB/SwissProt ID: G3X982 (G3X982)
Gene Name:
Aox3
Organism: Mus musculus (Mouse)
Function: Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and phthalazine, as well as aldehydes, such as benzaldehyde, retinal and pyridoxal. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. May also catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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