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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: FXYD domain-containing ion transport regulator

UniprotKB/SwissProt ID: F6TWM7 (F6TWM7)

Gene Name: Fxyd5

Organism: Mus musculus (Mouse)

Function: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. May increase NKA activity by increasing the apparent affinity for Na(+). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Basolateral cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR047297 FXYD_motif
IPR000272 Ion-transport_regulator_FXYD