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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Bifunctional cystathionine gamma-lyase/cysteine synthase

UniprotKB/SwissProt ID: F4K5T2 (F4K5T2)

Gene Name: DES1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Involved in maintaining Cys homeostasis through the desulfuration of L-cysteine. Modulates the generation of the signaling molecule sulfide in plant cytosol. Probably unable to interact with SAT and to form the decameric Cys synthase complex (CSC) and is therefore not an enzymatically true OASTL protein

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR005856 Cys_synth
IPR050214 Cys_Synth/Cystath_Beta-Synth
IPR005859 CysK
IPR001216 P-phosphate_BS
IPR001926 TrpB-like_PALP
IPR036052 TrpB-like_PALP_sf

The S-nitrosylation sites of F4K5T2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 30 MVYLNKIVDG C VARIAAKLEM