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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), chloroplastic

UniprotKB/SwissProt ID: F4K0E8 (F4K0E8)

Gene Name: ISPG

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Is essential for chloroplast development and required for the salicylic acid (SA)-mediated disease resistance to biotrophic pathogens

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Plastid, chloroplast stroma

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011005 Dihydropteroate_synth-like_sf
IPR017178 IspG_atypical
IPR004588 IspG_bac-typ
IPR045854 NO2/SO3_Rdtase_4Fe4S_sf

The S-nitrosylation sites of F4K0E8

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 147 TVQGKKEADA C FEIKDKLVQL   
2 356 TEPPEEEIDP C RRLANLGTKA