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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein CELLULOSE SYNTHASE INTERACTIVE 1

UniprotKB/SwissProt ID: F4IIM1 (F4IIM1)

Gene Name: CSI1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Regulator of the microtubular cytoskeleton (PubMed:22427339). Microtubule-associated protein essential for the functional association of cellulase synthase (CESA) complexes (CSCs) and cortical microtubules (PubMed:22190487, PubMed:22294619, PubMed:22751327, PubMed:23623553, PubMed:24368796). Promotes dynamics of CSCs in the plasma membrane (PubMed:20616083, PubMed:21150290, PubMed:22190487, PubMed:22294619, PubMed:22751327, PubMed:23623553, PubMed:24368796). Regulates primary cell wall biosynthesis and cellulose microfibrils organization (PubMed:20616083, PubMed:21150290, PubMed:23623553). Required for the regulation of root cell elongation/expansion (PubMed:20616083, PubMed:21150290, PubMed:22294619, PubMed:22427339, PubMed:7743935). Necessary for the formation of ovules, pollen cell wall morphogenesis and pollen tube development (PubMed:22294619). Involved in anther dehiscence, via dehydration-induced microtubule depolymerization and reorganization. May play a role in early gynoecial development (PubMed:22427339) Target of the cellulase synthase (CESA) complexes (CSCs) trafficking inhibitor CESTRIN, which reduces cellulose content and alters anisotropic growth of hypocotyls; CESTRIN treatment inhibits the dynamics of CSCs

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Golgi apparatus. Endomembrane system. Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR044297 CSI1/2/3

The S-nitrosylation sites of F4IIM1

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1756 ALLDLLRSHQ C EDTAARLLEV