UniprotKB/SwissProt ID: F4I1S7 (F4I1S7)
Gene Name:
ELP2
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity). Promotes organ development by modulating cell division rate. Prevents abscisic acid (ABA) signaling leading to stomatal closure and seedling growth inhibition. Involved in oxidative stress signaling. Prevents anthocyanin accumulation. Accelerator of defense gene induction required for rapid defense gene induction, and for the establishment of both basal and effector-triggered immunity (ETI), in a NPR1-independent manner, but is not required for systemic acquired resistance (SAR) establishment (PubMed:19500300, PubMed:20807211)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
|
|
|
