Protein Name:
Vacuolar-sorting protein BRO1
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UniprotKB/SwissProt ID: F4HXZ1 (F4HXZ1)
Gene Name:
BRO1
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen (Probable). Associates with FREE1 and ELC to perform function in the ESCRT-I complex. Binds ubiquitin in vitro (PubMed:26902184). Plays a role in the biogenesis of vacuole and multivesicular bodies (MVBs) (PubMed:26324913, PubMed:26342016). Required for the endosomal location of AMSH3 (PubMed:26324913). Mediates high-affinity phosphate transporter trafficking to maintain phosphate homeostasis. Regulates vacuolar degradation of PHT1-1 (PubMed:26342016)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Late endosome. Endosome, multivesicular body
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of F4HXZ1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
80 |
DLLISYYKVL C LVETRFPISP |
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