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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Inner nuclear membrane protein Man1

UniprotKB/SwissProt ID: F1LWZ8 (F1LWZ8)

Gene Name: Lemd3

Organism: Rattus norvegicus (Rat)

Function: Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus inner membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR052277 INM_ESCRT-Associated
IPR011015 LEM/LEM-like_dom_sf
IPR003887 LEM_dom
IPR018996 Man1/Src1-like_C
IPR034394 Man1_RRM
IPR041885 MAN1_winged_helix_dom
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf

The S-nitrosylation sites of F1LWZ8

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 352 EPGGGGGGGG C DQVDSIPRYR   
2 517 RLAQIAGDHE C GRSSQRMLSV   
3 724 VWRWVQPSAS C DKTSVIPSKV