UniprotKB/SwissProt ID: E9Q9F5 (E9Q9F5)
Gene Name:
Septin7
Organism: Mus musculus (Mouse)
Function: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Chromosome, centromere, kinetochore. Cleavage furrow. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, spindle. Midbody
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