Protein Name:
WD repeat- and FYVE domain-containing protein 4
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UniprotKB/SwissProt ID: E9Q2M9 (E9Q2M9)
Gene Name:
Wdfy4
Organism: Mus musculus (Mouse)
Function: Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells (PubMed:30409884). Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking (PubMed:30409884). Also plays a role in B-cell survival through regulation of autophagy (PubMed:30257884)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Early endosome. Endoplasmic reticulum
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of E9Q2M9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
227 |
ELQSLLIATT C LREHSCLFWK |
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