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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Vacuolar protein sorting-associated protein 26C

UniprotKB/SwissProt ID: E9PU42 (E9PU42)

Gene Name: Vps26c

Organism: Rattus norvegicus (Rat)

Function: Acts as a component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retriever and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR014752 Arrestin-like_C
IPR014756 Ig_E-set
IPR028934 Vps26-related

The S-nitrosylation sites of E9PU42

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 219 IELQLVRVET C GCAEGYARDA