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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Formylglycine-generating enzyme

UniprotKB/SwissProt ID: D4A7I8 (D4A7I8)

Gene Name: Sumf1

Organism: Rattus norvegicus (Rat)

Function: Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum lumen

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016187 CTDL_fold
IPR051043 Sulfatase_Mod_Factor_Kinase
IPR005532 SUMF_dom
IPR042095 SUMF_sf

The S-nitrosylation sites of D4A7I8

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 233 LPTEAEWEYS C RGGLQNRLFP