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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: GRIP and coiled-coil domain-containing protein 2

UniprotKB/SwissProt ID: D3ZZL9 (D3ZZL9)

Gene Name: Gcc2

Organism: Rattus norvegicus (Rat)

Function: Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2 (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Golgi apparatus, trans-Golgi network membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR032023 GCC2_Rab_bind
IPR000237 GRIP_dom
IPR051841 MT-Golgi_org_protein

The S-nitrosylation sites of D3ZZL9

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 311 TSDASQENQK C SVALQEDPFA