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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Zinc finger protein 462

UniprotKB/SwissProt ID: D3ZFG7 (D3ZFG7)

Gene Name: Zfp462

Organism: Rattus norvegicus (Rat)

Function: Zinc finger nuclear factor involved in transcription by regulating chromatin structure and organization. Involved in the pluripotency and differentiation of embryonic stem cells by regulating SOX2, POU5F1/OCT4, and NANOG. By binding PBX1, prevents the heterodimerization of PBX1 and HOXA9 and their binding to DNA. Regulates neuronal development and neural cell differentiation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050688 Zinc_finger/UBP_domain
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

The S-nitrosylation sites of D3ZFG7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1016 NTSPKTFTPE C ENQKDPSVNT   
2 1245 LCDRNQKPAS C VLLPASGMER   
3 1268 TKLRALKCRQ C SYTSPYFYAL   
4 1727 RHDIDAYYTH C LAASRTISDK   
5 1892 GPRFQNSTFQ C KHCDSKLQST   
6 1971 RKVVGYKCKF C VEVHPTLRAI   
7 2223 GGKKLFKCKD C SFYTGFKSAF   
8 625 RVHQQHKHSF C DNLPKFEGQP   
9 929 HSDLIYRCRF C SYTSPNVRSL