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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name:

UniprotKB/SwissProt ID: C9JZR9 (C9JZR9)

Gene Name: SLC30A6

Organism: Homo sapiens (Human)

Function: Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway. As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Golgi apparatus, trans-Golgi network membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002524 Cation_efflux
IPR027469 Cation_efflux_TMD_sf
IPR052005 CDF_SLC30A