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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: ATP-binding cassette sub-family C member 8

UniprotKB/SwissProt ID: B2RUS7 (B2RUS7)

Gene Name: Abcc8

Organism: Mus musculus (Mouse)

Function: Regulator subunit of pancreatic ATP-sensitive potassium channel (KATP), playing a major role in the regulation of insulin release. In pancreatic cells, it forms KATP channels with KCNJ11; KCNJ11 forms the channel pore while ABCC8 is required for activation and regulation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like_ATP-bd
IPR017871 ABC_transporter-like_CS
IPR050173 ABC_transporter_C-like
IPR000844 ABCC8
IPR000388 ABCC8/9
IPR027417 P-loop_NTPase

The S-nitrosylation sites of B2RUS7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 717 QLTMIVGQVG C GKSSLLLATL