Protein Name:
Carbon catabolite repressor protein 4 homolog 4
|
UniprotKB/SwissProt ID: A8MS41 (A8MS41)
Gene Name:
CCR4-4
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Transcriptional regulator of circadian rhythms with poly(A)-degrading activity that affects the expression and rhythmicity of the clock core oscillator genes TOC1 and CCA1 (PubMed:26619288). Deadenylation may be a mechanism involved in the regulation of the circadian clock (PubMed:26619288). May play a negative role in response against oxidative stress (PubMed:26619288). Possesses magnesium-dependent poly(A)-specific exoribonuclease activity in vitro and is almost inactive with poly(U), poly(C) and poly(G) as substrates (PubMed:26619288)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
