Protein Name:
Calcium-activated chloride channel regulator 1
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UniprotKB/SwissProt ID: A8K7I4 (A8K7I4)
Gene Name:
CLCA1
Organism: Homo sapiens (Human)
Function: May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted, extracellular space. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of A8K7I4
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
187 |
LSNGRIQAVR C SAGITGTNVV |
CCCHHHHHHH H HHHHHHHHHH |
2.35% |
25040305
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| 2 |
308 |
SLLQIGQRIV C LVLDKSGSMA |
CCCHHHHHHH H HHHHHHHHHH |
1.7% |
25040305
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