Protein Name:
Thiamine thiazole synthase, chloroplastic
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UniprotKB/SwissProt ID: A8J9T5 (A8J9T5)
Gene Name:
THI1
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Plastid, chloroplast
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Graphical Visualization of S-nitrosylation Sites:
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