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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glycerol-3-phosphate phosphatase

UniprotKB/SwissProt ID: A6NDG6 (A6NDG6)

Gene Name: PGP

Organism: Homo sapiens (Human)

Function: Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581). In vitro, also has a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036412 HAD-like_sf
IPR006357 HAD-SF_hydro_IIA
IPR023214 HAD_sf
IPR006349 PGP_euk

The S-nitrosylation sites of A6NDG6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 193 KALRYLQQPG C LLVGTNMDNR   
2 217 ENGRFIAGTG C LVRAVEMAAQ   
3 243 IGKPSRFIFD C VSQEYGINPE   
4 272 LDTDILLGAT C GLKTILTLTG   
5 297 GDVKNNQESD C VSKKKMVPDF   
6 35 LADVDTLLFD C DGVLWRGETA