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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Rho-related GTP-binding protein RhoU

UniprotKB/SwissProt ID: A5D7J5 (A5D7J5)

Gene Name: RHOU

Organism: Bos taurus (Bovine)

Function: Binds to and activates protein kinase PAK1. Plays a role in the regulation of cell morphology, cytoskeletal organization and focal adhesion assembly during cell migration. Also stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Golgi apparatus membrane. Cell junction, focal adhesion. Cell projection, podosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho