Protein Name:
Chloride intracellular channel protein 2
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UniprotKB/SwissProt ID: A2VE46 (A2VE46)
Gene Name:
CLIC2
Organism: Bos taurus (Bovine)
Function: In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Displays weak glutathione peroxidase activity. Can insert into membranes and form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Modulates the activity of RYR2 and inhibits calcium influx
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of A2VE46
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
30 |
AGSDGESIGN C PFSQRLFMIL |
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