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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Voltage-dependent N-type calcium channel subunit alpha

UniprotKB/SwissProt ID: A2AIR9 (A2AIR9)

Gene Name: Cacna1b

Organism: Mus musculus (Mouse)

Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. Mediates Ca(2+) release probability at hippocampal neuronal soma and synaptic terminals

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002048 EF_hand_dom
IPR031649 GPHH_dom
IPR005821 Ion_trans_dom
IPR014873 VDCC_a1su_IQ
IPR050599 VDCC_alpha-1_subunit
IPR005447 VDCC_N_a1su
IPR002077 VDCCAlpha1
IPR027359 Volt_channel_dom_sf