Protein Name:
SH3 and PX domain-containing protein 2B
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UniprotKB/SwissProt ID: A2AAY5 (A2AAY5)
Gene Name:
Sh3pxd2b
Organism: Mus musculus (Mouse)
Function: Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell projection, podosome
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Graphical Visualization of S-nitrosylation Sites:
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