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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Nidogen

UniprotKB/SwissProt ID: A1Z877 (A1Z877)

Gene Name: Ndg

Organism: Drosophila melanogaster (Fruit fly)

Function: Cell adhesion glycoprotein which is widely distributed in basement membranes (PubMed:30260959, PubMed:30567930). Involved in cell-extracellular matrix (ECM) interactions probably by connecting the laminin and collagen IV networks (PubMed:30260959, PubMed:30567930). Required for permeability and mechanical stability of basement membranes, and ECM dependent neural plasticity (PubMed:30567930). Not involved in assembly of the embryonic basement membrane (PubMed:30567930)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted. Secreted, extracellular space, extracellular matrix, basement membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011042 6-blade_b-propeller_TolB-like
IPR050778 Cueball_EGF_LRP_Nidogen
IPR001881 EGF-like_Ca-bd_dom
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR024731 EGF_dom
IPR006605 G2_nidogen/fibulin_G2F
IPR009017 GFP
IPR009030 Growth_fac_rcpt_cys_sf
IPR000033 LDLR_classB_rpt
IPR003886 NIDO_dom
IPR049883 NOTCH1_EGF-like