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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Pre-mRNA-processing factor 6

UniprotKB/SwissProt ID: A1A5S1 (A1A5S1)

Gene Name: Prpf6

Organism: Rattus norvegicus (Rat)

Function: Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleoplasm. Nucleus speckle

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003107 HAT
IPR010491 PRP1_N
IPR045075 Syf1-like
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_rpt

The S-nitrosylation sites of A1A5S1

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 513 REQWIQDAEE C DRAGSVATCQ   
2 522 ECDRAGSVAT C QAVMRAVIGI   
3 837 KTKSVDALKK C EHDPHVLLAV   
4 913 NAEPRHGELW C AVSKDITNWQ