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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: E1 ubiquitin-activating enzyme

UniprotKB/SwissProt ID: A0A3Q7I083 (A0A3Q7I083)

Gene Name: LOC101253520

Organism: Solanum lycopersicum (Tomato)

Function: Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR032420 E1_4HB
IPR032418 E1_FCCH
IPR042302 E1_FCCH_sf
IPR045886 ThiF/MoeB/HesA
IPR000594 ThiF_NAD_FAD-bd
IPR018965 Ub-activating_enz_E1_C
IPR042449 Ub-E1_IAD_1
IPR038252 UBA_E1_C_sf
IPR019572 UBA_E1_SCCH
IPR042063 Ubi_acti_E1_SCCH
IPR035985 Ubiquitin-activating_enz
IPR018075 UBQ-activ_enz_E1
IPR018074 UBQ-activ_enz_E1_CS
IPR033127 UBQ-activ_enz_E1_Cys_AS
IPR000011 UBQ/SUMO-activ_enz_E1-like

The S-nitrosylation sites of A0A3Q7I083

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 633 LLESGTLGAK C NTQMVIPHLT