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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Filamin-binding LIM protein 1

UniprotKB/SwissProt ID: A0A0G2K995 (A0A0G2K995)

Gene Name: Fblim1

Organism: Rattus norvegicus (Rat)

Function: Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell junction, focal adhesion. Cytoplasm, cytoskeleton, stress fiber

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001781 Znf_LIM

The S-nitrosylation sites of A0A0G2K995

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 335 ECMGRNFHEN C YRCEDCSVLL