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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Histone-lysine N-methyltransferase NSD3

UniprotKB/SwissProt ID: A0A0G2K001 (A0A0G2K001)

Gene Name: Nsd3

Organism: Rattus norvegicus (Rat)

Function: Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Chromosome. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006560 AWS_dom
IPR041306 C5HCH
IPR055198 NSD_PHD
IPR047456 PHD2_NSD3
IPR047458 PHD4_NSD3
IPR047527 PHD5_NSD3
IPR003616 Post-SET_dom
IPR000313 PWWP_dom
IPR047451 PWWP_NSD3_rpt1
IPR047453 PWWP_NSD3_rpt2
IPR050777 SET2_Histone-Lys_MeTrsfase
IPR001214 SET_dom
IPR046341 SET_dom_sf
IPR047461 SET_NSD3
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD

The S-nitrosylation sites of A0A0G2K001

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 634 QKGASEISDS C KPLKKRSRAS   
2 652 RASTDVETAS C TYRDTSDSDS   
3 736 GECCRHFHPE C LGLAAVPEGR