Protein Name:
CLIP-associating protein 1
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UniprotKB/SwissProt ID: A0A0G2JUI5 (A0A0G2JUI5)
Gene Name:
Clasp1
Organism: Rattus norvegicus (Rat)
Function: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Golgi apparatus, trans-Golgi network
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of A0A0G2JUI5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1230 |
EPIKRDGKKD C DIVSRDGGAA |
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| 2 |
883 |
TEDVAEVLNH C ASSNWSERKE |
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